Cytogenetic and molecular studies in the Prader-Willi and Angelman syndromes: an overview.
نویسندگان
چکیده
The majority of patients with Angelman syndrome and Prader-Willi syndrome have a cytogenetic and molecular deletion of chromosome 15q11q13 with the primary difference being in the parental origin of deletion. Our current understanding of the cytogenetics and molecular genetics of these 2 clinically distinct syndromes will be discussed in this review.
منابع مشابه
Progress in the autosomal segmental aneusomy syndromes (SASs): single or multi-locus disorders?
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ورودعنوان ژورنال:
- American journal of medical genetics
دوره 46 1 شماره
صفحات -
تاریخ انتشار 1993